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Januvia: Uses, Dosage, Side Effects

Since Januvia also works to lower blood sugar, drinking alcohol while you’re taking the drug may lead to hypoglycemia (low blood sugar). While taking Januvia, call your doctor if you develop soreness or pain in your joints, including severe joint pain. Your doctor may recommend treatments to help relieve this side effect. Or, they may have you stop taking Januvia and try a different medication. But unusually fast weight gain may be a sign of more severe side effects from Januvia.

  1. Your doctor will recommend the best strength for you to treat your type 2 diabetes.
  2. Depending on the dose of each drug you’re taking, you may be able to take Janumet.
  3. The clinical significance of this added increase in serum creatinine relative to placebo is not known.
  4. In addition, an active (glipizide)­controlled study of 52-weeks duration was conducted in 1172 patients with type 2 diabetes who had inadequate glycemic control on metformin.

This encourages your pancreas to release more insulin and stops your liver from releasing sugar into your blood, both of which can lower your blood sugar levels. When you digest food, your stomach and gut produce digestive hormones, called incretins, that signal your pancreas to secrete insulin. But as you continue to digest, these hormones are broken down by an enzyme called DPP-4.

Januvia (sitagliptin) is an oral diabetes medicine for people with type 2 diabetes (non-insulin-dependent) diabetes. Januvia is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes. Your doctor may prescribe JANUVIA alone or together with other diabetes medicines to help control blood sugar. Take JANUVIA exactly dmt uses, side effects, and risks as your doctor tells you and follow your doctor’s treatment plan for healthy eating and exercise. It may be harder to control your blood sugar when your body is stressed (such as due to fever, infection, injury, or surgery). Consult your doctor because increased stress may require a change in your treatment plan, medications, or blood sugar testing.

If I don’t have diabetes but want to lose weight, can I use Januvia?

The guidelines ensure that only a selected set of people are chosen due to time and costs. Other drugs may affect sitagliptin, including prescription and over-the-counter medicines, vitamins, and herbal products. ibuprofen and alcohol: is it safe to mix otc painkillers with alcohol Tell your doctor about all your current medicines and any medicine you start or stop using. It isn’t known whether people who have had pancreatitis before may be at higher risk for this side effect.

Got questions about JANUVIA?Get the facts from our FAQs.

Sitagliptin administered to female rats from gestation day 6 to lactation day 21 caused no functional or behavioral toxicity in offspring of rats at doses up to 1000 mg/kg. Assess renal function prior to initiation of JANUVIA and periodically thereafter. Our Januvia (sitagliptin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. You may be able to take advantage of prescription savings on JANUVIA. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed.

Elderly subjects (65 to 80 years) had approximately 19% higher plasma concentrations of sitagliptin compared to younger subjects. Elimination of sitagliptin occurs primarily via renal excretion and involves active tubular secretion. Sitagliptin is a substrate for human organic anion transporter-3 (hOAT-3), which may be involved in the renal elimination of sitagliptin.

Are Januvia and metformin the same?

Keeping a healthy weight is an important part of taking care of your diabetes. Most people who took JANUVIA by itself did not gain weight. JANUVIA, by itself, is not likely to cause hypoglycemia because it works less when your blood sugar is low. You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.

Another study suggested that certain people may have a higher risk of thyroid cancer with Januvia. If you have kidney problems, you might need renal dosing of Januvia. Your doctor will recommend the dosage of Januvia that’s right for you.

Is Januvia used for weight loss?

These programs potentially contribute to the variability of the quantity and quality of evidence supporting recent drug approvals.

Talk with your doctor or pharmacist about whether the dose of your other diabetes medication(s) needs to be lowered. Another natural alternative that’s been researched is the mineral chromium. But according to a review of clinical studies, it’s not clear whether chromium is effective and safe for treating high blood sugar caused by type 2 diabetes.

Postmarketing cases of bullous pemphigoid requiring hospitalization have been reported with DPP­4 inhibitor use. In reported cases, patients typically recovered with topical or systemic immunosuppressive treatment and discontinuation of the DPP-4 inhibitor. Tell patients to report development of blisters or erosions while receiving JANUVIA.

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